This paper concern the results of software fire spread process prototype in terminal 2 of Belgrade airport using computational fluid dynamics. Numerical simulation of fire for the most critical fire scenario has been performed, primarily obtaining the space and time distribution of: velocity, pressure, temperature, and smoke concentration, assuming that HVAC systems have been switched off and all doors on the evacuation ways have been opened, just as the fire started. Also, two simulations have been compared of the smoke ventilation and not ventilation for the same scenario. Within the framework of the results presentation, isosurfaces of constant temperature (100 ºC) and smoke concentration (4000 ppm) are presented, based on the numerical simulation. Progression of these surfaces along the terminal 2 coincides to the experimental and experience evidence, forming the plume zone just above the fireplace, and spreading in the zone of underground ceiling and stairwell openings. .