THERMAL SCIENCE

International Scientific Journal

Marko E. Popović

,

Gavrilo Šekularac

,

Vojin Tadić

,

Marijana Pantović-Pavlović

THE SILENT ASSASSIN: EMPIRICAL FORMULAS, MOLAR MASSES, BIOSYNTHESIS REACTIONS, ENTHALPIES, ENTROPIES AND GIBBS ENERGIES OF BIOSYNTHESIS AND GIBBS ENERGIES OF BINDING OF COXSACKIEVIRUSES A AND B

ABSTRACT
Coxsackievirus B represents a nightmare for a large number of medical staff. Due to exposure to Coxsackievirus in closed spaces (ambulances and waiting rooms), infections by Coxsackievirus B are a common occurrence. This paper for the first time reports chemical and thermodynamic properties of Coxsackieviruses A and B, and offers a mechanistic model of Coxsackievirus-host interaction. The driving force of the interaction at the membrane (antigen-receptor binding) is Gibbs energy of binding. The driving force of virus-host interaction in the cytoplasm is Gibbs energy of biosynthesis. This paper analyzes the mechanism of hijacking of cell metabolic machinery of susceptible cells.
KEYWORDS
Biothermodynamics, Bioenergetics, Virus-host interaction, Infectivity, Pathogenicity, Virus multiplication, Permissiveness, Susceptibility, Microorganism, Infection
PAPER SUBMITTED: 2024-04-29
PAPER REVISED: 2024-07-01
PAPER ACCEPTED: 2024-07-08
PUBLISHED ONLINE: 2024-10-12
DOI REFERENCE: https://doi.org/10.2298/TSCI240429213P
CITATION EXPORT: view in browser or download as text file
THERMAL SCIENCE YEAR 2024, VOLUME 28, ISSUE Issue 6, PAGES [4737 - 4757]
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The silent assassin: Empirical formulas, molar masses, biosynthesis reactions, enthalpies, entropies and Gibbs energies of biosynthesis and Gibbs energies of binding of Coxsackieviruses A and B

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